Grant Details

GRANT OVERVIEW

Grant name and funding organization

NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant

National Institutes of Health (NIH)

Total funding amount and duration

Funding amount is not limited but should reflect the actual needs of the proposed project.

Maximum project period is five years.

Primary objective and mission statement

To support investigator-initiated large-scale clinical trials related to vision disorders.

The mission of the NEI is to eliminate vision loss and improve quality of life through vision research.

Key stakeholders and beneficiaries

Investigators conducting clinical trials.

Participants in vision disorder studies.

Public health community focused on vision health.

ELIGIBILITY CRITERIA

Organization Requirements

Eligible organizations include higher education institutions, nonprofits, for-profit organizations, local and state governments, and federal agencies.

Non-domestic (non-U.S.) entities are also eligible to apply.

Geographic Scope

Open to U.S. and non-domestic entities.

Foreign components of U.S. organizations are allowed.

Project Requirements

Projects must evaluate interventions for vision disorders or compare effectiveness of established interventions.

Applications must propose clinical trials.

Financial Requirements

No specific budget limits, but budgets must reflect actual project needs.

Cost sharing is not required.

Timeline Requirements

Applications are due by 5:00 PM local time of applicant organization.

Key dates include multiple application due dates from 2023 to 2026.

Previous Funding Considerations

Applicant organizations may submit more than one application, provided each is scientifically distinct.

Duplicate applications under review at the same time are not accepted.

APPLICATION PROCESS

Required documentation and materials

Applications must follow the SF424 (R&R) Application Guide.

Specific attachments required include Statistical Analysis Plan, Data Handling, Quality Assurance, and Monitoring Plans.

Evaluation criteria and scoring system

Applications will be evaluated based on scientific and technical merit.

Review criteria include significance, investigator qualifications, innovation, approach, and environment.

Review process and timeline

Applications undergo peer review and are evaluated for completeness and compliance.

Expected timeline for review and award decisions is outlined in the grant announcement.

Selection criteria and priorities

Scientific merit and relevance to program priorities are key factors in funding decisions.

SPECIAL CONSIDERATIONS

Unique aspects or requirements

Substantial federal involvement is anticipated in project activities.

The Coordinating Center must provide scientific and technical leadership.

Potential challenges or limitations

Applications not responsive to the NOFO will be withdrawn without review.

Complex or high resource/safety-risk projects are prioritized.

Strategic alignment opportunities

Collaboration with other clinical centers and resource centers is encouraged.

Competitive advantages or disadvantages

Strong emphasis on data management and oversight may benefit well-organized applications.

KEY INSIGHTS AND RECOMMENDATIONS

Critical success factors

Clear delineation of roles and responsibilities in the study organization.

Strong leadership and oversight from the Coordinating Center.

Common pitfalls to avoid

Failure to comply with application instructions may lead to delays or rejection.

Submitting overlapping applications can result in disqualification.

Strategic recommendations for applicants

Engage with NIH staff early in the application process for guidance.

Ensure all required registrations are completed well in advance.

Competitive positioning advice

Highlight unique aspects of the proposed study and its potential impact on vision health.

Grant Details

clinical trials vision research healthcare public health cooperative agreements NIH funding nonprofit for-profit higher education foreign institutions
NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant (UG1 Clinical Trial Required)
PAR-23-204
NIH Grants
None
None
None
None
USD
None
May 25, 2026, 10 p.m.
March-May 2026