Grant Details

General Overview

Grant Name and Funding Organization

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers

National Cancer Institute (NCI), National Institutes of Health (NIH)

Total Funding Amount and Duration

Up to $100,000 per year for the K99 phase and up to $249,000 per year for the R00 phase.

Total project period may not exceed 5 years.

Primary Objective and Mission Statement

To increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators.

Facilitate timely transition from mentored postdoctoral positions to independent faculty positions.

Key Stakeholders and Beneficiaries

Early-stage postdoctoral researchers in cancer-related fields.

Institutions supporting these researchers.

Grant Program Context and History

Part of NIH's efforts to foster the transition of new investigators to research independence.

Funding Source and Type

Federal funding from the National Institutes of Health.

Grant mechanism.

Significance within Funding Landscape

Addresses the need for independent researchers in cancer research.

Grant Frequency

Recurring grant opportunity with multiple application deadlines.

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits (with and without 501(c)(3) status)

For-Profit Organizations

Governments (State, County, City, Tribal)

Other (e.g., Independent School Districts, Public Housing Authorities)

Specific Qualifications and Certifications Needed

Candidates must have a clinical or research doctorate (PhD, MD, etc.).

Organizational Size and Capacity Requirements

Not specified.

Geographic Location Requirements

U.S. institutions are eligible; foreign institutions are not.

Track Record and Experience Requirements

Candidates must have no more than 2 years of postdoctoral research experience.

Partnership or Consortium Requirements

Not specified.

Inclusivity and Diversity Considerations

Encouragement for recruiting individuals from underrepresented groups as mentors.

Previous Relationship with Funder Considerations

Not specified.

Organizational Maturity Requirements

The applicant institution must have a strong record of research and career development activities.

Scope and Focus

Primary Focus Areas and Priorities

Cancer control, cancer prevention, and cancer data sciences.

Target Sectors and Themes

Biomedical, behavioral, and clinical research.

Target Beneficiaries and Stakeholders

Early-stage postdoctoral researchers.

Geographic Coverage Requirements

U.S.-based institutions only.

Scope Limitations and Exclusions

Research involving leading independent clinical trials is not allowed.

Expected Outcomes and Deliverables

Transition to independent tenure-track faculty positions.

Alignment Requirements with Funder Priorities

Research must align with NCI's mission.

Impact Expectations

Enhancement of research capabilities in cancer-related fields.

Project Scale Requirements

K99 phase supports up to 2 years of mentored training; R00 phase supports up to 3 years of independent research.

Sustainability Expectations

Not specified.

Technical Details

Technical Expertise Requirements

Candidates must have a strong background in biomedical, behavioral, or clinical research.

Infrastructure Requirements

The institution must provide sufficient research support and facilities.

Team Composition and Qualification Requirements

Candidates must identify a mentor with relevant expertise.

Research Methodology Requirements

Not specified.

Quality Standards and Expectations

Research must be scientifically sound and significant.

Technical Documentation Requirements

Applications must follow the SF424 (R&R) Application Guide.

Risk Management Expectations

Not specified.

Intellectual Property Policies

Not specified.

Technology Specifications

Not specified.

Technical Partnerships Expectations

Not specified.

Security and Data Protection Requirements

Not specified.

Technical Compliance Standards

Must comply with NIH Grants Policy Statement.

Financial Structure

Budget Range and Limitations

K99 phase: up to $100,000 per year; R00 phase: up to $249,000 per year.

Eligible and Ineligible Costs

Salary and research-related expenses are eligible; salary for mentors is not allowed.

Matching Fund Requirements and Percentages

Not specified.

Co-Financing Requirements

Not specified.

Payment Schedule and Mechanisms

Not specified.

Financial Reporting Requirements

Must comply with NIH Grants Policy Statement.

Audit Requirements

Not specified.

Financial Sustainability Expectations

Not specified.

Cost-Sharing Structures

Not required.

Indirect Cost Policies

8% for K99 phase; R00 phase reimbursed at the institution’s indirect cost rate.

Budget Flexibility Parameters

Not specified.

Financial Guarantees Required

Not specified.

Timeline and Implementation

Application Deadlines and Submission Windows

Earliest submission date: January 14, 2024.

Multiple application deadlines until October 14, 2026.

Grant Duration Parameters

Total project period may not exceed 5 years.

Implementation Timeline Expectations

K99 phase supports up to 2 years; R00 phase supports up to 3 years.

Reporting Schedule and Frequency

Annual progress reports required.

Key Milestones and Deliverables Timeline

Transition to independent faculty position by the end of the K99 phase.

Monitoring and Evaluation Requirements

Evaluation of progress during the K99 phase.

Implementation Phases Requirements

Continuous transition from K99 to R00 phases.

Extension Possibilities

Limited exceptions may be possible.

Project Planning Requirements

Must include a detailed career development plan.

Progress Tracking Mechanisms

Annual evaluations by mentors.

Post-Grant Period Expectations

Not specified.

Compliance and Requirements

Regulatory Compliance Requirements

Must comply with NIH Grants Policy Statement.

Required Permits and Authorizations

Not specified.

Data Protection and Privacy Regulations

Not specified.

Environmental Compliance Requirements

Not specified.

Ethical Standards and Requirements

Must adhere to ethical standards in research.

International Collaboration Regulations

Not specified.

Industry-Specific Regulatory Compliance

Not specified.

Labor Standards Compliance

Not specified.

Tax Implications and Requirements

Not specified.

Reporting Compliance Requirements

Must comply with NIH reporting requirements.

Accessibility and Inclusion Standards

Not specified.

Legal Framework Compliance

Must comply with federal regulations.

Application Process

Required Documentation and Materials

Institutional nomination letter, project summary, budget information, and mentor statements.

Application Procedure and Steps

Applications must be submitted electronically via Grants.gov.

Evaluation Criteria and Scoring System

Applications evaluated based on scientific merit and potential for independent research.

Review Process and Timeline

Applications undergo peer review and advisory council review.

Selection Criteria and Priorities

Focus on candidates' potential for independent research careers.

Pre-Application Requirements

Candidates are encouraged to confirm eligibility with NCI.

Submission Format and Platform

Use NIH ASSIST or Grants.gov Workspace for submission.

Supporting Materials Required

Mentor statements and letters of support from collaborators.

Interview or Presentation Requirements

Not specified.

Application Assistance Availability

Contact NCI for assistance.

Resubmission Policies

Resubmissions allowed under specific conditions.

Special Considerations

Unique Aspects or Requirements

Focus on early-stage postdoctoral researchers.

Potential Challenges or Limitations

Limited to candidates with minimal postdoctoral experience.

Strategic Alignment Opportunities

Aligns with NCI's mission to advance cancer research.

Competitive Advantages Factors

Strong mentorship and institutional support are critical.

Cross-Cutting Themes

Encouragement for diversity in mentorship.

Innovation Requirements or Preferences

Encouraged to propose creative research.

Research Component Requirements

Research must not involve leading independent clinical trials.

Risk Tolerance and Mitigation Expectations

Not specified.

Cultural and Contextual Considerations

Not specified.

Knowledge Sharing Expectations

Not specified.

Previous Funding Patterns

Historical Grant Recipients Profile

Not specified.

Success Rate Statistics

Not specified.

Grant Size Trends

Not specified.

Recurring Grantee Patterns

Not specified.

Geographic Distribution Patterns

Not specified.

Sector Concentration Patterns

Not specified.

Emerging Priority Areas

Focus on cancer-related research.

Changes in Funding Criteria Over Time

Not specified.

Success Stories and Case Studies

Not specified.

Lessons Learned from Previous Cycles

Not specified.

Grant Details

cancer tumor research healthcare biomedical clinical research postdoctoral mentorship career development independent research
NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers
PAR-23-286
NCI Pathway to Independence Award
EDU NGO PUBLIC RESEARCH OTHER
US
HEALTHCARE OTHER
DEVELOPMENT OTHER
0-10 11-50 51-250 251-500 500+
SDG3
FUNDING MENTORSHIP RESEARCH_DEVELOPMENT
None
None
100000.00
249000.00
USD
None
Oct. 14, 2026, 5 p.m.
Not specified