Grant Details

GRANT OVERVIEW

Grant name and funding organization

NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)

National Institutes of Health (NIH)

Total funding amount and duration

Funding amount is not limited but must reflect the actual needs of the proposed project.

Maximum project period is 5 years.

Primary objective and mission statement

To support basic science experimental studies involving humans.

To foster fundamental discoveries and innovative research strategies that improve health.

Key stakeholders and beneficiaries

Investigators and researchers in health-related fields.

Human participants involved in the studies.

ELIGIBILITY CRITERIA

Organization Requirements

Eligible organization types include higher education institutions, nonprofits, for-profit organizations, local governments, and tribal governments.

Non-domestic (non-U.S.) entities are eligible to apply.

Geographic Scope

Open to U.S. and non-domestic organizations.

Project Requirements

Projects must involve basic science experimental studies with human participants.

Studies must meet the NIH definition of a clinical trial.

Financial Requirements

No cost-sharing is required.

Application budgets are not limited but must reflect actual project needs.

Timeline Requirements

Applications are due by 5:00 PM local time of the applicant organization.

Key application deadlines include January 5, 2025, and subsequent dates for renewals.

Previous Funding Considerations

Organizations may submit more than one application as long as they are scientifically distinct.

The NIH will not accept duplicate or overlapping applications.

APPLICATION PROCESS

Required documentation and materials

Applications must follow the instructions in the How to Apply - Application Guide.

Specific forms and documents as outlined in the guide must be submitted.

Evaluation criteria and scoring system

Applications will be evaluated based on scientific and technical merit.

Review criteria include significance, innovation, and approach.

Review process and timeline

Applications undergo peer review and are assigned to appropriate NIH Institutes or Centers.

Selection criteria and priorities

Scientific merit and relevance to program priorities are key factors in funding decisions.

SPECIAL CONSIDERATIONS

Unique aspects or requirements

Applications must propose studies that meet the NIH definition of a clinical trial.

Potential challenges or limitations

Applicants must ensure compliance with all application instructions to avoid delays.

Strategic alignment opportunities

Applicants are encouraged to contact relevant NIH staff to discuss research interests.

Competitive advantages or disadvantages

Strong applications that align with NIH priorities are more likely to receive funding.

KEY INSIGHTS AND RECOMMENDATIONS

Critical success factors

Clear alignment with NIH scientific missions and priorities.

Strong research design and methodology.

Common pitfalls to avoid

Submitting overlapping applications.

Failing to adhere to application guidelines.

Strategic recommendations for applicants

Engage with NIH staff early in the application process.

Ensure all registrations are completed prior to submission.

Competitive positioning advice

Highlight unique aspects of the proposed research that align with NIH goals.

Grant Details

health clinical trial basic research human studies biomedical research behavioral research nonprofit higher education for-profit government
NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
PA-25-303
NIH Grants
EDU NGO ENTERPRISE PUBLIC OTHER
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RESEARCH_DEVELOPMENT
False
None
None
None
USD
None
True
True
The expected impact includes fostering innovative research strategies and improving health outcomes through basic science studies.
Specific outputs include research findings that contribute to the understanding of health-related phenomena.
Jan. 7, 2028, 10 p.m.
March 2025
Follow the instructions in the How to Apply - Application Guide.
True
Applications will be evaluated based on scientific and technical merit.
Significance and innovation of the proposed research.
Rigor and feasibility of the proposed approach.
Potential for the project to exert a sustained, powerful influence on the research field.
False
False
Grant
Recipients must comply with NIH Grants Policy Statement and other applicable regulations.
Annual reporting through Research Performance Progress Report (RPPR).
Details of payment arrangements are outlined in the NIH Grants Policy Statement.
All NIH awards are subject to federal regulations and NIH Grants Policy Statement.
No additional sector-specific requirements are mentioned.