Grant Details

General Overview

Grant Information

Grant name: Blueprint Neurotherapeutics Network (BPN)

Funding organization: National Institutes of Health (NIH)

Total funding amount: Not specified

Duration: Up to 5 years (1 year for UG3 phase, up to 4 years for UH3 phase)

Primary objective: Advance small molecule drug discovery and development projects into clinical settings.

Key stakeholders: Neuroscience investigators, NIH consultants, CROs.

Funding source: NIH.

Funding type: Cooperative Agreement.

Significance: Supports drug discovery in neuroscience, filling a gap in resources for academic labs and small companies.

Grant frequency: Recurring.

Organizational Aspects

Eligibility Criteria

Eligible organization types: Higher Education Institutions, Nonprofits, For-Profit Organizations, Local Governments, State Governments, County Governments, City or Township Governments, Indian/Native American Tribal Governments, Federal Government, Foreign Organizations.

Specific qualifications: Not specified.

Geographic location requirements: Not specified.

Track record: Not specified.

Partnership requirements: Collaboration with NIH consultants and CROs is encouraged.

Inclusivity and diversity considerations: Not specified.

Previous relationship with funder: Not specified.

Scope and Focus

Project Focus

Primary focus areas: Small molecule drug discovery and development for nervous system disorders.

Target sectors: Neuroscience, pharmacology.

Expected outcomes: Development of drug candidates through IND-enabling studies and Phase I clinical testing.

Sustainability expectations: Not specified.

Technical Details

Requirements

Technical expertise: Experience in medicinal chemistry and drug development.

Infrastructure requirements: Access to laboratories and necessary research tools.

Quality standards: Compliance with Good Manufacturing Practices (GMP) and FDA standards.

Risk management: Not specified.

Financial Structure

Funding Details

Budget range: Not specified.

Eligible costs: Costs associated with drug discovery and development activities.

Matching fund requirements: Not specified.

Payment schedule: Not specified.

Financial reporting requirements: Not specified.

Timeline and Implementation

Key Dates

Application deadlines: New applications due by 5:00 PM local time on specified dates.

Earliest start date: January 27, 2025.

Expiration date: August 19, 2026.

Compliance and Requirements

Regulatory Compliance

Regulatory compliance requirements: Must adhere to NIH policies and FDA regulations.

Data protection regulations: Not specified.

Application Process

Submission Guidelines

Required documentation: Follow instructions in the Research Instructions in the How to Apply - Application Guide.

Application procedure: Submit through Grants.gov or NIH ASSIST system.

Evaluation criteria: Based on scientific merit and alignment with NIH priorities.

Special Considerations

Unique Aspects

Potential challenges: High attrition rates in drug development.

Innovation requirements: Projects should propose novel approaches to drug discovery.

Previous Funding Patterns

Historical Context

Success rate statistics: Not specified.

Emerging priority areas: Focus on neuroscience and small molecule development.

Grant Details

neuroscience drug discovery small molecules clinical trials healthcare pharmaceuticals research development medicinal chemistry
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System
PAR-25-051
Blueprint Neurotherapeutics Network
EDU NGO ENTERPRISE PUBLIC RESEARCH OTHER
US
HEALTHCARE OTHER
IDEA DEVELOPMENT
0-10 11-50 51-250 251-500 500+
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
None
None
None
USD
None
July 15, 2025, 5 p.m.
Not specified