BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain
National Institutes of Health (NIH)
$6 million total funding
Maximum budget of $700,000 per application
Maximum project period of 3 years
To support exploratory research using invasive neural recording and stimulating technologies in the human brain.
Researchers in neuroscience and related fields
Patients undergoing neurosurgical procedures
Part of the BRAIN Initiative aimed at advancing neurotechnologies since 2014.
Federal funding from the NIH
Grant type: R61 Phase 1 Exploratory/Developmental Grant
Addresses high-impact questions in human neuroscience.
One-time funding opportunity with specific application deadlines.
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
For-Profit Organizations
Small Businesses
Local Governments
State Governments
County Governments
City or Township Governments
Indian/Native American Tribal Governments (Federally Recognized)
Federal Government Eligible Agencies
Must propose basic science experimental studies involving humans.
Organizations must be based in the U.S.
Foreign institutions are not eligible to apply.
Applicants must demonstrate skills, knowledge, and resources necessary to carry out the proposed research.
Multidisciplinary teams are encouraged, but not explicitly required.
Applications must address inclusion of diverse populations in research.
Not specified
Exploratory research in human neuroscience using invasive technologies.
Patients undergoing neurosurgical procedures.
Researchers in neuroscience.
Establish feasibility, proof-of-principle, and early-stage development.
Multidisciplinary expertise including clinicians, scientists, and regulatory specialists.
Plans for addressing technical, procedural, and ethical aspects specific to invasive studies.
Maximum budget of $700,000 per application.
Direct costs only, excluding facilities and administrative costs for consortia.
Application due date: September 19, 2025.
Must comply with NIH Grants Policy Statement.
Neuroethics considerations and team management plan.
Must address neuroethical considerations.
Not specified