Grant Details

GRANT OVERVIEW

Grant name and funding organization

Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required)

National Institutes of Health (NIH)

Total funding amount and duration

Total project period may not exceed 5 years.

Funding amounts are contingent upon NIH appropriations.

Primary objective and mission statement

To support outstanding basic or clinical investigators in developing independent research skills.

Facilitate the transition of NINDS intramural neurologist- and neurosurgeon-scientists to independent academic faculty positions.

Key stakeholders and beneficiaries

NINDS intramural neurologists and neurosurgeons.

Academic institutions and research communities.

ELIGIBILITY CRITERIA

Organization Requirements

Eligible organization types include higher education institutions, nonprofits, for-profit organizations, and local/state governments.

Only NINDS may apply for the initial mentored phase on behalf of intramural neurologists or neurosurgeons.

Geographic Scope

Only U.S.-based organizations are eligible to apply.

Non-domestic entities (foreign organizations) are not eligible.

Project Requirements

Applicants must propose to serve as the lead investigator of an independent clinical trial.

The research plan must span both phases of the award.

Financial Requirements

NINDS will contribute up to $125,000 per year toward the salary of the career award recipient during the extramural phase.

Indirect costs are reimbursed at 8% of modified total direct costs.

Timeline Requirements

Application due dates are set for various cycles, with the next due date on June 12, 2025.

All applications are due by 5:00 PM local time of the applicant organization.

Previous Funding Considerations

Individuals are not eligible if they have had any individual NIH career development award or are currently a PD/PI on an NIH research grant.

APPLICATION PROCESS

Required documentation and materials

Applicants must follow the instructions in the Career Development (K) Instructions in the How to Apply - Application Guide.

Evaluation criteria and scoring system

Applications are evaluated for scientific and technical merit through the NIH peer review system.

Review process and timeline

Applications will undergo a selection process based on scientific merit and relevance to program priorities.

Selection criteria and priorities

Overall impact, candidate potential, career development plan, and research plan are key evaluation criteria.

SPECIAL CONSIDERATIONS

Unique aspects or requirements

The award is specifically for candidates proposing to serve as the lead investigator of an independent clinical trial.

Potential challenges or limitations

Transition from the intramural phase to the extramural phase requires administrative approval.

Strategic alignment opportunities

Candidates are encouraged to develop a comprehensive career development plan with their mentors.

Competitive advantages or disadvantages

Candidates must demonstrate a strong commitment to a career in biomedical or behavioral research.

KEY INSIGHTS AND RECOMMENDATIONS

Critical success factors

Strong mentorship and institutional support are crucial for success.

Common pitfalls to avoid

Ensure compliance with all application instructions to avoid delays or rejection.

Strategic recommendations for applicants

Develop a clear and coherent career development plan tailored to individual needs.

Competitive positioning advice

Highlight unique research contributions and potential for independent funding.

Grant Details

research clinical trial neurology neurosurgery career development scientific research healthcare academic faculty independent research
Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required)
PAR-25-216
NIH Research Career Development
PUBLIC NGO EDU ENTERPRISE OTHER
US
RESEARCH_DEVELOPMENT
False
None
None
None
USD
None
True
True
Facilitate the transition of clinician-scientists to independent research careers.
Successful completion of the research plan and submission of an NIH R01 application by the end of the fourth year.
Nov. 12, 2027, 10 p.m.
March 2025 - November 2027
Follow the instructions in the Career Development (K) Instructions in the How to Apply - Application Guide.
True
Peer review based on scientific and technical merit.
Proposed research must address significant questions in the field.
Research plan must be appropriate for the candidate's stage of development.
Potential for a productive, independent scientific research career.
False
False
Grant
Recipients must comply with NIH Grants Policy Statement.
Annual progress reports and final RPPR required.
Details of payment arrangements will be outlined in the Notice of Award.
NIH Grants Policy Statement applies.
Specific to neuroscience and clinical research.