Grant Details

General Overview

Grant Name and Funding Organization

NEI Small Business Innovation Research (SBIR) Cooperative Agreement for Early-Stage Clinical Trials with Greater than Minimal Risk (U44)

National Eye Institute (NEI), National Institutes of Health (NIH)

Total Funding Amount and Duration

Up to $1,000,000 per year, total project cost not exceeding $2,000,000

Maximum duration of three years

Primary Objective and Mission Statement

Support SBCs in conducting early-stage clinical trials focused on screening, diagnosing, preventing, or treating vision disorders.

Mission of NEI is to eliminate vision loss and improve quality of life through vision research.

Key Stakeholders and Beneficiaries

Small business concerns (SBCs)

Individuals with vision disorders

Funding Source and Type

Federal funding from the National Institutes of Health (NIH)

Cooperative agreement mechanism

Grant Frequency

Recurring funding opportunity

Organizational Aspects

Eligible Organization Types

Small business concerns (SBCs) organized for profit

Specific Qualifications and Certifications Needed

Must meet the NIH definition of a clinical trial

Evidence of FDA Investigational New Drug (IND) or Investigational Device Exemption (IDE) application submission required

Geographic Location Requirements

Must be based in the United States

Organizational Size and Capacity Requirements

Must have not more than 500 employees

Previous Relationship with Funder Considerations

Not specified

Scope and Focus

Primary Focus Areas and Priorities

Clinical trials for vision disorders

Expected Outcomes and Deliverables

Completion of clinical trials with safety and efficacy data

Sustainability Expectations

Commercialization plan required

Technical Details

Technical Expertise Requirements

Expertise in conducting clinical trials

Risk Management Expectations

Safety monitoring and oversight required

Financial Structure

Budget Range and Limitations

Up to $1,000,000 per year, total project cost not exceeding $2,000,000

Eligible and Ineligible Costs

Costs related to the conduct of clinical trials are eligible

Timeline and Implementation

Application Deadlines

Applications due by 5:00 PM local time of applicant organization

Grant Duration Parameters

Maximum duration of three years

Compliance and Requirements

Regulatory Compliance Requirements

Must comply with FDA regulations for IND/IDE

Application Process

Required Documentation and Materials

Clinical protocol, commercialization plan, data management plans

Evaluation Criteria and Scoring System

Scientific merit and alignment with NEI mission

Grant Details

clinical trials vision disorders small business healthcare research innovation biotechnology
NEI Small Business Innovation Research (SBIR) Cooperative Agreement for Early-Stage Clinical Trials with Greater than Minimal Risk (U44)
PAR-24-066
Small Business Innovation Research (SBIR)
SME STARTUP
US
HEALTHCARE TECHNOLOGY
DEVELOPMENT
0-10 11-50 51-250 251-500
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
2000000.00
1000000.00
1000000.00
USD
100.00
May 27, 2026, 10 p.m.
March 2024 - April 2024