Grant name: In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains
Funding organization: National Institutes of Health (NIH)
Total funding amount: Up to $499,999 per year
Duration: Maximum project period of 5 years
Primary objective: Encourage research on embryonic lethal knockout mouse strains
Key stakeholders: NIH, research community, and public health
Grant program context: Part of the NIH Knockout Mouse Phenotyping Program (KOMP2)
Funding source: NIH
Funding type: Grant
Significance: Supports research on congenital diseases and structural birth defects
Grant frequency: Recurring
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
For-Profit Organizations
Small Businesses
Local Governments
State Governments
County Governments
City or Township Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Governments
U.S. Territory or Possession
Other: Independent School Districts, Public Housing Authorities, Faith-based Organizations, Regional Organizations, Foreign Organizations
Applicant organizations must complete registrations with SAM, eRA Commons, and Grants.gov.
All Program Directors/Principal Investigators (PDs/PIs) must have an eRA Commons account.
In-depth phenotyping of embryonic lethal knockout mouse strains
Research on placental defects, structural birth defects, and fertility issues
Comprehensive catalogue of mammalian gene function
Functional analyses of human genetic variation
Experience in phenotyping and genetic research
Ability to utilize KOMP2/IMPC resources
Maximum budget: $499,999 per year
No cost-sharing required
Earliest submission date: May 5, 2025
Latest application due date: October 5, 2025
Compliance with NIH Grants Policy Statement
Adherence to ethical standards and data management policies
Follow instructions in the Research (R) Instructions in the How to Apply - Application Guide
Submission through Grants.gov