New Approaches for Measuring Brain Changes Across Longer Timespans
National Institutes of Health (NIH)
Maximum funding amount: $275,000 over two years
Project period: Maximum of 2 years
Encourage multidisciplinary investigators to develop novel approaches to measure brain activity and connectivity.
Extend understanding of brain development and aging.
Researchers in neuroscience and related fields.
Participants including healthy individuals and specific clinical groups.
Reissue of PAR-24-161.
Aligned with NIH priorities.
NIH funding source.
Type: Exploratory/Developmental Research Grant (R21).
Focus on high-risk, high-reward research.
Recurring grant opportunity with multiple application deadlines.
Higher Education Institutions
Public/State Controlled Institutions
Private Institutions of Higher Education
Nonprofits (with and without 501(c)(3) status)
For-Profit Organizations
Small Businesses
Local, State, County, and City Governments
Indian/Native American Tribal Governments
Federal Agencies
Foreign Organizations
Must complete registrations with SAM, eRA Commons, and Grants.gov.
Open to U.S. and foreign organizations.
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Encourages diverse participation in research.
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Innovative approaches to measure brain changes.
Longitudinal studies across the lifespan.
Neuroscience, aging, cognitive health.
Healthy individuals, clinical groups with cognitive challenges.
Global, with emphasis on U.S. and foreign entities.
Studies without in vivo measurements will not be reviewed.
Innovative methods and tools for brain measurement.
Projects should align with NIH's mission and priorities.
Significant advancements in understanding brain health and disease.
Must include at least two timepoints in each participant or animal.
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Expertise in neuroscience, brain imaging, and related fields.
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Must include qualified Program Director(s)/Principal Investigator(s).
Must include innovative approaches to brain measurement.
Adherence to NIH guidelines for rigor and transparency.
Must follow application instructions in the Application Guide.
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Managed according to NIH policies.
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Compliance with data protection regulations.
Must comply with NIH Grants Policy Statement.
Direct costs limited to $275,000 over two years.
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Must comply with NIH reporting standards.
Must comply with NIH audit requirements.
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Earliest submission date: January 16, 2025.
Multiple application due dates through 2027.
Maximum project period: 2 years.
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Annual progress reports required.
Must include annual milestones.
Must comply with NIH evaluation standards.
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Must follow application instructions.
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Must comply with federal regulations.
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Must comply with data protection regulations.
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Must adhere to ethical research standards.
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Must comply with NIH reporting standards.
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Must comply with applicable laws.
Must follow application instructions in the Application Guide.
Applications must be submitted electronically.
Applications evaluated for scientific and technical merit.
Applications undergo peer review and advisory council review.
Scientific merit and relevance to program priorities.
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Must use Grants.gov or NIH ASSIST.
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eRA Service Desk available for assistance.
Must follow NIH resubmission policies.
Encourages high-risk, high-reward research.
Non-responsive applications will not be reviewed.
Aligns with NIH's mission.
Focus on innovative methodologies.
Encourages diversity and inclusion in research.
Must demonstrate novel approaches.
Must include at least two timepoints.
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