Grant Details

GRANT OVERVIEW

Grant Name and Funding Organization

Planning for Product Development Strategy (R34 Clinical Trial Not Allowed)

National Institutes of Health (NIH)

Total Funding Amount and Duration

Estimated funding amount: $225,000 per year

Maximum project period: 1 year

Primary Objective and Mission Statement

Support the development of comprehensive product development strategies for next-generation treatments for HIV.

Facilitate the translation of research findings into drug products for IND applications.

Key Stakeholders and Beneficiaries

Public and private nonprofit institutions

Individuals involved in biomedical research

Patients with HIV and associated comorbidities

ELIGIBILITY CRITERIA

Organization Requirements

Eligible organization types include higher education institutions, nonprofits, for-profit organizations, and tribal governments.

Specific qualifications include being a public or state-controlled institution, private institution, or nonprofit with or without 501(c)(3) status.

Geographic Scope

Eligible organizations can be based in the U.S. or be foreign organizations.

Non-domestic components of U.S. organizations are also eligible.

Project Requirements

Projects must focus on HIV treatment or prevention, or HIV-associated comorbidities.

Applications proposing clinical trials are not allowed.

Financial Requirements

Application budgets are limited to $225,000/year in direct costs.

No cost-sharing is required.

Timeline Requirements

Application due date: December 4, 2026.

Open date for submissions: February 13, 2025.

Previous Funding Considerations

Applicant organizations may submit more than one application, provided each is scientifically distinct.

The NIH will not accept duplicate or overlapping applications.

APPLICATION PROCESS

Required Documentation and Materials

Applications must follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.

Specific forms include SF424(R&R) Cover and Project/Performance Site Locations.

Evaluation Criteria and Scoring System

Applications will be evaluated based on scientific and technical merit.

Review criteria include importance of the research, rigor and feasibility, and expertise and resources.

Review Process and Timeline

Applications will undergo peer review and receive a written critique.

Funding decisions will consider scientific merit and relevance to program priorities.

Selection Criteria and Priorities

Applications deemed to have the highest scientific and technical merit will be prioritized.

SPECIAL CONSIDERATIONS

Unique Aspects or Requirements

Applications must not propose clinical trials.

A well-defined product development strategy is essential.

Potential Challenges or Limitations

Complexities in drug development require multidisciplinary expertise and partnerships.

Strategic Alignment Opportunities

Collaboration with Contract Research Organizations (CROs) and regulatory professionals is recommended.

Competitive Advantages or Disadvantages

Strong emphasis on innovative approaches to HIV treatment and prevention.

KEY INSIGHTS AND RECOMMENDATIONS

Critical Success Factors

Develop a comprehensive and well-defined product development strategy.

Engage a multidisciplinary team with relevant expertise.

Common Pitfalls to Avoid

Avoid submitting overlapping applications.

Ensure compliance with all application instructions.

Strategic Recommendations for Applicants

Start the registration process early to avoid delays.

Consider potential funding gaps and plan accordingly.

Competitive Positioning Advice

Highlight innovative aspects of the proposed product development strategy.

Grant Details

hiv biomedical research health drug development clinical trials nonprofit public health infectious diseases product development strategy
Planning for Product Development Strategy (R34 Clinical Trial Not Allowed)
PAR-25-099
NIH Grants
PUBLIC NGO ENTERPRISE RESEARCH OTHER
US AF AL DZ AS AD AO AI AQ AG AR AU AT BY BE BG CA CN HR CY CZ DK EG EE FI FR GE DE GI GR HU IS IE IL IT JP LV LI LT LU MK MY MT MX MD NL NZ NO PL PT QA RO SA SC SG SK SI ES SE CH TR UA AE UK VA VG VI
RESEARCH_DEVELOPMENT
False
1000000.00
None
225000.00
USD
100.00
True
False
Advancing biomedical research and improving treatment options for HIV and associated comorbidities.
A comprehensive product development strategy that enables IND submission.
Dec. 4, 2026, 10 p.m.
March 2025 - July 2027
Follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.
True
Applications will be evaluated based on scientific and technical merit.
Applications must demonstrate innovative approaches to HIV treatment and prevention.
Applications must outline a feasible product development strategy.
Applications must show potential for significant impact on HIV treatment and prevention.
True
True
Grant
Recipients must comply with NIH Grants Policy Statement.
Annual reporting required for progress and financial statements.
Details of payment arrangements will be outlined in the Notice of Award.
Awards are made under the authorization of the Public Health Service Act.
Compliance with NIH Grants Policy Statement is required.