Grant name: Integrating Biospecimen Science Approaches into Clinical Assay Development
Funding organization: National Institutes of Health (NIH), National Cancer Institute (NCI)
Total funding amount: $250,000 per year
Duration: Maximum of 5 years
Primary objective: To investigate and mitigate challenges in clinical assay development due to preanalytical variability in biospecimens.
Key stakeholders: Clinical researchers, academic and private sector scientists.
Significance: Aims to improve biomarker clinical assay development through standardization of biopsy handling practices.
Grant frequency: Recurring.
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
For-Profit Organizations
Small Businesses
Local Governments
State Governments
County Governments
City or Township Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Foreign Organizations
Organizations must complete registrations with SAM, eRA Commons, and Grants.gov.
Principal Investigators must have an eRA Commons account.
Research on preanalytical variability in tumor tissue biopsies and blood biospecimens.
Improvement of biomarker assay reliability.
Evidence-based standardization of biospecimen handling practices.
Improved understanding of biomarker quantification.
Multidisciplinary teams including pathologists, oncologists, radiologists, and molecular biologists.
Application budgets are limited to $250,000 direct costs per year.
No cost-sharing is required.
Open Date: January 04, 2025
Application Due Dates: Various dates including June 04, 2025, September 10, 2025, February 04, 2026, and others until September 11, 2027.
Must comply with NIH Grants Policy Statement and other federal regulations.
Applications must be submitted electronically via Grants.gov.
Follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.