Grant Details

General Overview

Grant Information

Grant name: Assay Validation of High Quality Markers for Clinical Studies in Cancer

Funding organization: National Institutes of Health (NIH), National Cancer Institute (NCI)

Total funding amount: Up to $275,000 for UH2 phase; Up to $250,000 per year for UH3 phase

Duration: UH2 phase up to 2 years; UH3 phase up to 3 years

Primary objective: Support validation of biomarkers and assays for cancer-related studies

Funding source: Federal government

Funding type: Cooperative agreement

Significance: Addresses critical needs in cancer research and clinical trials

Grant frequency: One-time funding opportunity

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Small Businesses

Local Governments

State Governments

County Governments

City or Township Governments

Indian/Native American Tribal Governments (Federally Recognized)

Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Governments

Eligible Agencies of the Federal Government

U.S. Territory or Possession

Other: Independent School Districts, Public Housing Authorities, Faith-based Organizations

Ineligibility

Non-domestic (non-U.S.) Entities are not eligible to apply.

Non-domestic components of U.S. Organizations are not eligible.

Scope and Focus

Primary Focus Areas

Validation of molecular/cellular/imaging markers for cancer detection, diagnosis, prognosis, and treatment response.

Support for investigator-initiated research for analytical and clinical validation of assays.

Technical Details

Technical Expertise Requirements

Applicants must have assays that work on human samples.

Assays must be justified for development into clinical assays.

Financial Structure

Budget Information

Applicants may request up to $275,000 direct costs for the UH2 phase.

No more than $200,000 can be requested in any one year for UH2.

Up to $250,000 direct costs for the UH3 phase per year.

Timeline and Implementation

Key Dates

Open Date: January 14, 2025

Application Due Dates: Various dates from June 11, 2025 to October 14, 2026

Expiration Date: October 15, 2026

Compliance and Requirements

Regulatory Compliance

Compliance with NIH Grants Policy Statement is required.

Assays must be performed in CLIA-certified laboratories if intended for medical decision-making.

Application Process

Submission Requirements

Applications must be submitted electronically through Grants.gov.

Adherence to the application instructions in the Research Instructions is critical.

Grant Details

cancer biomarkers clinical trials healthcare research assay validation medical research oncology clinical studies biotechnology
Assay Validation of High Quality Markers for Clinical Studies in Cancer
PAR-25-074
NIH Grants
EDU NGO ENTERPRISE SME PUBLIC OTHER
US
HEALTHCARE OTHER
DEVELOPMENT
0-10 11-50 51-250 251-500 500+
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
None
275000.00
250000.00
USD
None
Oct. 15, 2026, 10 p.m.
March 2025 - July 2027