Grant Details

Grant Overview

Grant Name and Funding Organization

Exploratory/Developmental Bioengineering Research Grants (EBRG)

National Institutes of Health (NIH)

Total Funding Amount and Duration

Total budget: $275,000 over a maximum of 2 years

No more than $200,000 in any single year

Primary Objective and Mission Statement

To encourage submissions of exploratory/developmental Bioengineering Research Grant applications.

To demonstrate feasibility and potential utility of new capabilities or improvements in biomedical research.

Key Stakeholders and Beneficiaries

Biomedical researchers

Healthcare providers

Patients and communities benefiting from improved biomedical solutions

Eligibility Criteria

Organization Requirements

Eligible organization types include higher education institutions, nonprofits, for-profit organizations, and various levels of government.

Specific qualifications include having the skills, knowledge, and resources necessary to carry out the proposed research.

Geographic Scope

Eligible organizations can be based in the U.S. or be foreign organizations.

Non-domestic components of U.S. organizations are also eligible.

Project Requirements

Projects must demonstrate feasibility and potential utility of new capabilities.

Research may include hypothesis-driven, discovery-driven, developmental, or design-directed approaches.

Financial Requirements

Total direct costs for the two-year project period may not exceed $275,000.

No more than $200,000 may be requested in any single year.

Timeline Requirements

Application due date: January 7, 2028.

Projects must be completed within a maximum of 2 years.

Previous Funding Considerations

Applicants may submit more than one application, provided each is scientifically distinct.

The NIH will not accept duplicate or overlapping applications under review at the same time.

Application Process

Required Documentation and Materials

Applications must follow the instructions in the How to Apply - Application Guide.

Specific forms and templates must be used as outlined in the application instructions.

Evaluation Criteria and Scoring System

Applications will be evaluated based on significance, innovation, rigor, feasibility, and expertise of the investigators.

Review Process and Timeline

Applications will undergo peer review and will be evaluated for scientific and technical merit.

Selection Criteria and Priorities

Applications will compete for available funds based on scientific merit and relevance to program priorities.

Special Considerations

Unique Aspects or Requirements

Projects must not propose clinical trials.

Applications that do not demonstrate feasibility or potential utility may be considered nonresponsive.

Potential Challenges or Limitations

Projects may face risks associated with feasibility tests and early development.

Strategic Alignment Opportunities

Encourages multidisciplinary approaches to biomedical challenges.

Competitive Advantages or Disadvantages

Innovative approaches may provide a competitive edge in addressing biomedical problems.

Key Insights and Recommendations

Critical Success Factors

Demonstrating the significance and potential impact of the proposed work.

Common Pitfalls to Avoid

Submitting applications that do not comply with the application instructions.

Strategic Recommendations for Applicants

Engage in multidisciplinary collaborations to enhance project feasibility.

Competitive Positioning Advice

Highlight innovative aspects of the proposed research to stand out in the review process.

Grant Details

bioengineering healthcare biomedical research clinical research innovation feasibility studies health technology research grants NIH funding
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)
PAR-25-346
NIH Grants
EDU NGO ENTERPRISE PUBLIC OTHER
US AF AL DZ AS AD AO AI AQ AG AR AU AT BY BE BG CA CN HR CY CZ DK EG EE FI FR GE DE GI GR HU IS IE IL IT JP LV LI LT LU MK MY MT MX MD NL NZ NO PL PT QA RO SA SC SG SK SI ES SE CH TR UA AE UK VA VG VI
RESEARCH_DEVELOPMENT
False
275000.00
None
200000.00
USD
None
True
False
The grant aims to improve biomedical research and clinical care delivery through innovative bioengineering solutions.
Specific outputs include feasibility studies, preliminary data, and innovative solutions to biomedical challenges.
Jan. 7, 2028, 10 p.m.
January 2028
Applications must include all required forms as specified in the How to Apply - Application Guide.
True
Applications will be evaluated based on significance, innovation, rigor, feasibility, and expertise.
Innovation is defined as a credible research strategy for successful early steps toward delivery of a new capability.
Feasibility will be assessed based on the proposed plan, timeline, and performance targets.
Impact will be evaluated based on the potential to significantly advance knowledge in biomedical research.
False
False
Grant
Recipients must comply with NIH Grants Policy Statement and other applicable regulations.
Annual reporting is required, including a final RPPR and financial statements.
Details of payment arrangements will be outlined in the Notice of Award.
All NIH awards are subject to the terms and conditions described in the NIH Grants Policy Statement.
No additional sector-specific requirements are mentioned.