Grant name: Precision Approaches in Radiation Synthetic Combinations (PAIRS, R01 Clinical Trial Optional)
Funding organization: National Institutes of Health (NIH), National Cancer Institute (NCI)
Total funding amount: Not specified
Duration: Maximum project period of 5 years
Primary objective: Investigate actionable synthetic vulnerabilities paired with tumor responses to radiation therapy
Key stakeholders: Researchers, cancer patients, healthcare providers
Funding source: Federal government
Funding type: Grant
Significance: Aims to enhance precision medicine in cancer treatment
Grant frequency: Recurring until September 8, 2025
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits (with and without 501(c)(3) status)
For-Profit Organizations
Small Businesses
Local Governments
State Governments
County Governments
City or Township Governments
Special District Governments
Indian/Native American Tribal Governments (Federally Recognized and Other)
Federal Government Agencies
U.S. Territories or Possessions
Other (e.g., Independent School Districts, Public Housing Authorities, Faith-based Organizations, Regional Organizations, Foreign Institutions)
Development of radiation-synthetic combination strategies
Pre-clinical research to early clinical trials
Targeting intrinsic vulnerabilities triggered by radiation treatment
Emphasis on holistic radiobiology perspective
Expertise in cancer biology, radiobiology, and targeted therapeutics
Ability to conduct pre-clinical and clinical research
Application budgets are not limited but must reflect actual project needs
Open Date: September 05, 2022
Application Due Dates: Multiple deadlines until September 8, 2025
All applications due by 5:00 PM local time of applicant organization
Compliance with NIH Grants Policy Statement
Required registrations: SAM, eRA Commons, Grants.gov
Applications must be submitted electronically via Grants.gov
Follow SF424 (R&R) Application Guide instructions
Applications not integrating radiation into the treatment design will not be reviewed