Grant name: Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
Funding organization: National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA)
Total funding amount: Up to $500,000 for R61 phase; R33 phase budget is not limited but must reflect actual needs.
Duration: Maximum of 5 years (2 years for R61 phase, 3 years for R33 phase)
Primary objective: To support exploratory and developmental clinical research on neurobiological mechanisms of substance use disorders.
Funding source: Federal government (NIH)
Funding type: Grant
Significance: Addresses critical public health issues related to substance use disorders.
Grant frequency: Recurring (multiple application deadlines)
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits (with and without 501(c)(3) status)
For-Profit Organizations
Small Businesses
Local, State, County, City or Township Governments
Indian/Native American Tribal Governments (both federally recognized and others)
Federal Government Agencies
U.S. Territories or Possessions
Other: Independent School Districts, Public Housing Authorities, Faith-based Organizations, Regional Organizations, Foreign Institutions
All PD(s)/PI(s) must have an eRA Commons account.
Applicant organizations must complete registrations with SAM, eRA Commons, and Grants.gov.
Understanding neurobiological mechanisms underlying substance use disorders.
Exploratory studies on neural circuitry and behavior related to substance use.
Innovative methodologies to enhance health-related research.
Development of novel techniques, methodologies, and applications impacting SUD research.
Quantitative milestones for assessing progress.
Applicants are encouraged to include preliminary data if available.
Proposed milestones should be quantitative and clinically meaningful.
R61 phase budget: Combined direct costs may not exceed $500,000 for up to 2 years.
R33 phase budget: Not limited but must reflect actual project needs.
Open Date: May 21, 2023
Application Due Dates: Multiple deadlines from June 21, 2023, to March 13, 2026.
Expiration Date: May 08, 2026
Compliance with NIH Grants Policy Statement is required.
Data Management and Sharing Plan must be included.
Applications must be submitted electronically via Grants.gov.
Follow the SF424 (R&R) Application Guide for detailed instructions.