Grant name: BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
Funding organization: National Institutes of Health (NIH)
Total funding amount: Estimated total of $8 million
Duration: Maximum project period of three years
Primary objective: Facilitate translation of novel recording and modulation technologies for CNS diseases
Key stakeholders: Researchers, clinicians, patients
Funding source: Federal government
Funding type: Grant
Significance: Supports innovative neurotechnologies for CNS disorders
Grant frequency: One-time funding opportunity
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits (with and without 501(c)(3) status)
For-Profit Organizations
Small Businesses
Local Governments
State Governments
County Governments
City or Township Governments
Special District Governments
Indian/Native American Tribal Governments (Federally Recognized and Other)
Federal Government Agencies (including NIH Intramural Program)
Independent School Districts
Public Housing Authorities
Faith-based or Community-based Organizations
Regional Organizations
Foreign Organizations (non-domestic entities)
Non-domestic components of U.S. Organizations
Development of novel recording and modulation technologies for CNS
Technologies may include electrical, optical, magnetic, and acoustic modalities
Encourages synchronization with other technologies in real-time
Demonstration of basic functionality and potential of the technology
Preparation for future GLP testing or clinical studies
Validation of technology or approach in vivo
Team-based applications integrating various domains of expertise are encouraged
Involvement of engineering, computational, and scientific expertise
Application budgets are not limited but should reflect actual needs
Budgets should rarely exceed $750,000 direct costs per year
Open Date: April 29, 2024
Application Due Date: January 28, 2027
Expiration Date: January 29, 2027
Follow NIH Grants Policy Statement
No clinical trials allowed under this NOFO
Needs Assessment
Intellectual Property Strategy
Team Management Plan
Gantt Chart
Current State-of-the-Art Statement