Grant Details

General Overview

Funding Information

Funding Organization: National Institutes of Health (NIH)

Total Funding Amount: Not specified

Duration: Maximum project period of 4 years

Primary Objective: Support rigorous analytical validation of biomarkers for neurological and neuromuscular disorders.

Context and History

This is a reissue of PAR-24-095.

The funding opportunity was updated to align with agency priorities.

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Small Businesses

Local Governments

State Governments

County Governments

City or Township Governments

Indian/Native American Tribal Governments (Federally Recognized)

Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Government Agencies

U.S. Territory or Possession

Other: Independent School Districts, Public Housing Authorities, Faith-based Organizations, Regional Organizations

Ineligibility

Non-domestic (non-U.S.) Entities are not eligible to apply.

Non-domestic components of U.S. Organizations are not eligible to apply.

Scope and Focus

Primary Focus Areas

Validation of biomarkers for neurological and neuromuscular disorders.

Applications must justify the unmet need for the biomarker(s) and measurement methods.

Expected Outcomes

Optimizing and evaluating the accuracy, precision, reportable range, and analytical sensitivity and specificity of detection methods.

Technical Details

Technical Expertise Requirements

Multi-disciplinary collaboration among scientific investigators, developers, clinicians, and statisticians is encouraged.

Financial Structure

Budget Information

Application budgets are not limited but should reflect the actual needs of the proposed project.

Timeline and Implementation

Submission Deadlines

Application Due Date: June 22, 2026

Open Date: January 21, 2025

Compliance and Requirements

Regulatory Compliance

All applications must comply with NIH Grants Policy Statement.

Application Process

Required Documentation

Applications must follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.

Grant Details

biomarker neurological disorders neuromuscular disorders clinical trials healthcare research validation cooperative agreements NIH NINDS
Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional)
PAR-25-050
NIH Grants
EDU NGO PUBLIC RESEARCH ENTERPRISE SME OTHER
US
HEALTHCARE RESEARCH
DEVELOPMENT
0-10 11-50 51-250 251-500 500+
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
None
None
None
USD
None
June 22, 2026, 10 p.m.
Not specified