Grant Details

General Overview

Grant Information

Grant name: Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)

Funding organization: National Institutes of Health (NIH)

Total funding amount: Up to $275,000

Duration: Maximum project period of 2 years

Primary objective: Enhance knowledge of mechanisms associated with neuropsychiatric symptoms in Alzheimer's disease and related dementias

Key stakeholders: NIH, NIMH, NIA, researchers in the field

Funding source: NIH

Funding type: Grant

Significance: Addresses urgent need for better treatments for neuropsychiatric symptoms in dementia

Grant frequency: One-time

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Small Businesses

Local Governments

State Governments

County Governments

City or Township Governments

Indian/Native American Tribal Governments (Federally Recognized)

Indian/Native American Tribal Governments (Other than Federally Recognized)

Foreign Organizations

Specific Qualifications

Must have an active registration in System for Award Management (SAM)

Must have an eRA Commons account for Program Directors/Principal Investigators

Scope and Focus

Primary Focus Areas

Neurobiological and behavioral mechanisms underlying neuropsychiatric symptoms

Integration of multiple levels of analysis in research

Target Beneficiaries

Individuals with Alzheimer's disease and related dementias

Technical Details

Technical Expertise Requirements

Research in biomedical, behavioral, and social sciences

Experience with neuroimaging, neurophysiology, gene expression, and behavioral intervention research

Financial Structure

Budget and Funding

Maximum budget for direct costs: $275,000

Maximum request in any single year: $200,000

Timeline and Implementation

Key Dates

Open Date: January 16, 2025

Application Due Dates: February 16, 2025; June 16, 2025; October 16, 2025; February 16, 2026; June 16, 2026

Compliance and Requirements

Regulatory Compliance

Must comply with NIH Grants Policy Statement

Must follow ethical standards and regulations for human subjects research

Application Process

Required Documentation

Follow instructions in the Research (R) Instructions in the How to Apply - Application Guide

Submission through Grants.gov

Grant Details

healthcare research neuropsychiatric symptoms alzheimer's disease dementia biomedical research behavioral research social sciences
Novel Mechanism Research on Neuropsychiatric Symptoms in Alzheimer's Dementia
PAR-25-064
NIH Grants
EDU NGO ENTERPRISE PUBLIC RESEARCH OTHER
US
HEALTHCARE OTHER
DEVELOPMENT
0-10 11-50 51-250 251-500 500+
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
275000.00
None
200000.00
USD
None
June 16, 2026, 10 p.m.
Not specified