Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
National Institutes of Health (NIH)
Total budget for direct costs may not exceed $275,000 for a two-year project period.
No more than $200,000 may be requested in any single year.
To support innovative basic and translational pilot research projects aligned with NIH HIV/AIDS research priorities.
Focus on understanding biological, behavioral, and social mechanisms contributing to HIV pathogenesis.
Researchers in the field of HIV/AIDS.
Institutions involved in biomedical research related to diabetes, digestive, and kidney diseases.
Eligible organization types include Higher Education Institutions, Nonprofits, For-Profit Organizations, Local Governments, State Governments, County Governments, City or Township Governments, and Indian/Native American Tribal Governments.
Non-domestic (non-U.S.) entities are not eligible to apply.
Applications are limited to organizations based in the United States.
Non-domestic components of U.S. organizations are not eligible.
Projects must focus on basic or translational HIV research within the mission of NIDDK.
Applications proposing clinical trials are not accepted.
The combined budget for direct costs for the two-year project period may not exceed $275,000.
No more than $200,000 may be requested in any single year.
Application deadline is January 7, 2028.
All applications are due by 5:00 PM local time of the applicant organization.
Applicant organizations may submit more than one application, provided each is scientifically distinct.
The NIH will not accept duplicate or highly overlapping applications under review at the same time.
Applications must follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.
Applications will be evaluated based on scientific and technical merit through the NIH peer review system.
Applications will undergo a selection process based on scientific merit and relevance to program priorities.
Overall impact score reflecting the likelihood of the project to influence the research field.
Projects must address NIH HIV/AIDS research priorities as outlined by the NIH Office of AIDS Research.
Non-responsive applications will be administratively withdrawn without review.
Encouragement for applicants to contact NIDDK staff for guidance on project alignment with NIDDK's mission.
Understanding of health-impeding social determinants of health is crucial for project success.
Alignment with NIH HIV/AIDS research priorities.
Strong scientific merit and innovative approach.
Submitting applications that do not comply with the application instructions.
Engage with NIDDK staff early in the application process.
Focus on unique aspects of the proposed research that align with NIDDK's mission.