This grant supports educational outreach activities for health professionals, focusing on disseminating research findings related to alcohol and other substance use disorders.
- It aims to improve clinical practice and patient care by enhancing healthcare providers' understanding of current research in this area.
- SECTOR-SPECIFIC: Healthcare, Public Health, Research Education.
- Geographic scope: Organizations located in the United States. No foreign entities or components.
- Key filtering criteria: Focus on professional education, not clinical trials; specific to alcohol/substance use; U.S.-based applicant.
- Grant frequency: Recurring with multiple application deadlines until May 2026; a reissue of a previous program.
Financial Structure
Application budgets must not exceed $250,000 direct costs per year.
Project period is 4 years.
No matching fund requirements or cost sharing.
Indirect Costs are reimbursed at 8% of modified total direct costs.
Eligible costs include: personnel salaries and fringe benefits (within caps), justified participant compensation (per diem, partial tuition, education-related expenses), consultant costs, equipment, supplies, and travel for key personnel.
Ineligible costs include: full-time participant support (40 hours/week, 12 months), salary/stipend supplementation for NIH training/career development award recipients.
Eligibility Requirements
Organization Type
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits with 501(c)(3) IRS Status
Nonprofits without 501(c)(3) IRS Status
Small Businesses
For-Profit Organizations (Other than Small Businesses)
Local Governments
State Governments
County Governments
City or Township Governments
Special District Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Government Agencies
U.S. Territory or Possession
Independent School Districts
Public Housing Authorities/Indian Housing Authorities
Native American Tribal Organizations (other than Federally recognized tribal governments)
Faith-based or Community-based Organizations
Regional Organizations
Geographic Location
Applicant must be located in the United States.
Non-domestic (non-U.S.) entities (Foreign Institutions) are not eligible.
Non-domestic components of U.S. Organizations are not eligible.
Foreign components are not allowed.
Qualifications and Certifications
Must complete and maintain active registrations with:
Sponsoring institution must assure support and adequate staff, facilities, and educational resources.
Institutions with existing federal training grants (e.g., T32) may apply if proposed educational experiences are distinct from those already federally supported.
Exclusions
Clinical trials are not allowed.
Cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.
Costs to support full-time participants (40 hours/week for a continuous, 12-month period) are not allowable.
Application Process
Key Dates and Deadlines
Application Due Dates (latest): May 25, 2026 (by 5:00 PM local time of applicant organization).
Letter of Intent Due Date: 30 days before application due date (optional but requested).
Submission Procedure
Applications must be submitted electronically via NIH ASSIST, Grants.gov Workspace, or an institutional system-to-system (S2S) solution.
All required registrations (SAM, UEI, eRA Commons, Grants.gov) must be completed prior to submission.
Applicants are encouraged to submit early to allow time for error correction.
Notify the NIAAA Referral Office by email after submission.
Required Documentation
SF424 (R&R) Application Guide and program-specific instructions must be followed.
Research Education Program Plan, including:
Proposed Research Education Program
Program Director/Principal Investigator details
Program Faculty details
Program Participants details
Institutional Environment and Commitment
Plan for Instruction in the Responsible Conduct of Research (RCR)
Evaluation Plan
Dissemination Plan
Letter of institutional commitment (as part of Letters of Support).
Software Dissemination Plan (if supporting software development).
PHS Human Subjects and Clinical Trials Information form (if applicable).
Post-Award Requirements
Annual Research Performance Progress Report (RPPR).
Annual financial statements.
Reporting to Federal Subaward Reporting System (FSRS) for subawards over the threshold.
Maintaining current information in System for Award Management (SAM) regarding civil, criminal, and administrative proceedings.
Submission of Statement of Appointment (PHS Form 2271) and Termination Notice (PHS Form 416-7) for participants.
Evaluation Criteria
Overall Impact
Likelihood for the project to strongly advance research education by fulfilling the goal of this program.
Scored Review Criteria
Significance: Does the project address an important problem? How will it advance the education field?
Investigators: Are the PD/PI(s) and program faculty well-suited and experienced? Is there appropriate leadership for multiple PD/PIs?
Innovation: Does the project employ novel concepts, approaches, or methods? Are the aims original and transformative?
Approach: Are the overall strategy, methodology, and analyses well-reasoned and appropriate? Are potential problems addressed? (Includes specific sub-criteria for education program plan components)
Proposed Research Education Program: Is it distinct from currently federally supported training?
Program Director/Principal Investigator: Evidence of active engagement in research/teaching and ability to administer/monitor/evaluate.
Program Faculty: Research expertise and experience relevant to the program.
Program Participants: Clear description of intended participants, eligibility, and career levels.
Institutional Environment and Commitment: Adequate staff, facilities, and educational resources; strong institutional support.
Plan for Instruction in the Responsible Conduct of Research (RCR): Must include specific components (format, subject matter, faculty participation, duration, frequency) and be appropriate for program. Applications lacking this plan will not be reviewed.
Evaluation Plan: Specifies baseline metrics and measures for short/long-term success, and how feedback will be gathered and implemented.
Dissemination Plan: Specific plan to disseminate findings and materials nationally.
Environment: Does the institutional environment contribute to the probability of success? Are resources available?
Protections for Human Subjects: Justification for involvement and proposed protections.
Inclusion of Women, Minorities, and Individuals Across the Lifespan: Plans for inclusion/exclusion justification.
Vertebrate Animals: Justification for use and care.
Biohazards: Assessment of potential hazards and protection.
Training in Methods for Enhancing Reproducibility: Instruction plan on scientific premise, experimental design, biological variables, resource authentication, data sharing, record keeping, transparency.
Resource Sharing Plans: Reasonableness of plan or rationale for not sharing; software dissemination plan assessment (if applicable).
Budget and Period of Support: Justification and reasonableness of budget in relation to proposed work.
Compliance & Special Requirements
Regulatory Compliance
Adherence to NIH Grants Policy Statement and Federal Regulations (42 CFR Part 52, 45 CFR Part 75, 2 CFR Part 200).
Compliance with HHS civil rights laws (nondiscrimination based on race, color, national origin, age, sex, disability), conscience laws, and ensuring meaningful access for limited English proficient individuals and persons with disabilities.
Compliance with Federal Awardee Performance and Integrity Information System (FAPIIS) requirements.
Ethical and Quality Standards
Mandatory plan for instruction in the Responsible Conduct of Research (RCR), covering format (face-to-face required), subject matter, faculty participation, duration, and frequency.
Adherence to ethical guidelines for human subjects research (IRB/IEC approval required).
Data and Intellectual Property
Data Management and Sharing Plan is not applicable for this NOFO (for due dates on or after January 25, 2023, general NIH policy applies but specifically noted as not applicable here).
If software development is supported, a software dissemination plan is required, aiming for free availability to non-profit biomedical researchers/educators and permitting commercialization of enhanced versions.
Unique Program Aspects
This grant is specifically for Outreach educational activities to practicing health professionals.
Clinical trials are explicitly not allowed.
Emphasis on 'creative and novel approaches' beyond basic brochures or toolkits.
Applications addressing health disparities or medically underserved populations are encouraged.
A sustainability plan is a required component of the application.
Grant Details
alcohol use disorder
substance use disorder
opioid use disorder
health professionals
medical education
biomedical research
behavioral research
clinical research
outreach programs
public health
healthcare education
continuing medical education
addiction treatment
prevention strategies
health disparities
medically underserved populations
us government grants
nih grants
r25 grant
education projects
Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)
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