Grant Details

General Overview

Grant Name and Funding Organization

Innovation Grants to Nurture Initial Translational Efforts (IGNITE)

Department of Health and Human Services, National Institutes of Health (NIH)

Total Funding Amount and Duration

Direct costs cannot exceed $499,000 in any one year.

Cumulative direct costs for the entire three-year project period may not exceed $750,000.

Primary Objective and Mission Statement

Encourages research grant applications to develop in vitro, ex vivo, or in vivo assays and conduct iterative screening efforts to identify and characterize potential therapeutic agents for neurological or neuromuscular disorders.

Key Stakeholders and Beneficiaries

Researchers in the field of neurology and neuromuscular disorders.

Patients suffering from neurological or neuromuscular disorders.

Funding Source and Type

National Institutes of Health (NIH)

Grant funding

Grant Frequency

Recurring grant opportunity with multiple application deadlines.

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Small Businesses

Local Governments

State Governments

County Governments

City or Township Governments

Indian/Native American Tribal Governments (Federally Recognized)

Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Government Agencies

U.S. Territories or Possessions

Faith-based or Community-based Organizations

Regional Organizations

Non-domestic (non-U.S.) Entities (Foreign Organizations)

Geographic Location Requirements

Organizations from the U.S. and foreign organizations are eligible.

Track Record and Experience Requirements

Applicants must demonstrate the skills, knowledge, and resources necessary to carry out the proposed research.

Scope and Focus

Primary Focus Areas and Priorities

Development of assays for neurological and neuromuscular disorders.

Expected Outcomes and Deliverables

Identification and characterization of potential therapeutic agents.

Sustainability Expectations

Plans for future therapeutic discovery efforts beyond the project period.

Technical Details

Technical Expertise Requirements

Investigators are encouraged to form multidisciplinary teams.

Quality Standards and Expectations

Emphasis on rigor and transparency in research.

Financial Structure

Budget Range and Limitations

Direct costs cannot exceed $499,000 in any one year.

Cumulative direct costs for the entire three-year project period may not exceed $750,000.

Timeline and Implementation

Application Deadlines and Submission Windows

Open Date: January 18, 2025

Multiple application deadlines through 2027.

Compliance and Requirements

Regulatory Compliance Requirements

Must comply with NIH Grants Policy Statement.

Application Process

Required Documentation and Materials

Applications must include a detailed research plan and milestones.

Grant Details

neurology neurotherapeutics research healthcare biomedical research assay development therapeutic agents innovation translational research
Innovation Grants to Nurture Initial Translational Efforts (IGNITE)
PAR-25-059
NIH Innovation Grants
EDU NGO ENTERPRISE SME PUBLIC RESEARCH OTHER
US
HEALTHCARE OTHER
DEVELOPMENT OTHER
0-10 11-50 51-250 251-500 500+
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
750000.00
None
499000.00
USD
100.00
Oct. 21, 2027, 5 p.m.
March 2025 - July 2028