Grant Details

General Overview

Grant Information

Grant name: Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV

Funding organization: National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA)

Total funding amount: $2.5 million

Funding duration: Up to 5 years

Primary objective: To examine protein interaction networks in HIV-infected microglia and their role in SUD and HIV comorbidity.

Funding Context

This is a reissue of RFA-DA-25-014.

The grant is part of NIH's efforts to address the intersection of HIV and substance use disorders.

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits (with and without 501(c)(3) status)

For-Profit Organizations

Small Businesses

Local, State, County, City, and Township Governments

Indian/Native American Tribal Governments (both recognized and non-recognized)

Federal Government Agencies

U.S. Territories or Possessions

Other organizations including Independent School Districts, Public Housing Authorities, Faith-based Organizations, and Foreign Organizations.

Required Registrations

Organizations must register with System for Award Management (SAM), eRA Commons, and Grants.gov before applying.

Scope and Focus

Research Objectives

Investigate protein interaction networks in microglia affected by HIV and SUD.

Utilize quantitative analytical approaches and in vivo models for research.

Expected Outcomes

Generate foundational knowledge for potential therapeutic interventions targeting HIV and SUD comorbidity.

Technical Details

Technical Expertise Requirements

Applicants should demonstrate expertise in quantitative protein profiling and relevant methodologies.

Financial Structure

Budget Information

Application budgets are not limited but must reflect actual project needs.

Timeline and Implementation

Key Dates

Open Date: July 14, 2025

Application Deadline: July 14, 2025

Earliest Start Date: August 14, 2025

Expiration Date: August 15, 2025

Compliance and Requirements

Regulatory Compliance

Applicants must comply with NIH Grants Policy Statement and other federal regulations.

Application Process

Submission Instructions

Applications must be submitted electronically via Grants.gov or NIH ASSIST.

A letter of intent is encouraged but not required.

Grant Details

healthcare research substance use disorder HIV microglial pathophysiology biomedical research public health nonprofits higher education for-profit organizations
Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV (R61/R33 Clinical Trial Not Allowed)
RFA-DA-25-063
National Institute on Drug Abuse (NIDA) Funding
EDU NGO ENTERPRISE PUBLIC RESEARCH OTHER
US
HEALTHCARE RESEARCH
DEVELOPMENT
0-10 11-50 51-250 251-500 500+
SDG3 SDG4
FUNDING RESEARCH_DEVELOPMENT
None
2500000.00
None
None
USD
None
July 14, 2025, 10 p.m.
Not specified