Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional)
National Institutes of Health (NIH)
Funding amount is not limited but should reflect the actual needs of the proposed project.
Maximum project period is 5 years.
To invite applications proposing research on current topics in Alzheimer's disease (AD) and its related dementias (ADRD).
To encourage biomedical, social, and behavioral research directed toward understanding the aging process and related diseases.
Researchers in the field of Alzheimer's disease and related dementias.
Individuals affected by Alzheimer's disease and their families.
Eligible organization types include higher education institutions, nonprofits, for-profit organizations, local governments, state governments, and tribal governments.
Nonprofits must have 501(c)(3) status or not have such status.
Foreign organizations are eligible to apply.
Open to U.S. and non-U.S. entities.
Non-domestic components of U.S. organizations are eligible.
Research must focus on Alzheimer's disease and related dementias.
Applications must propose scientifically distinct projects.
Application budgets are not limited but must reflect actual project needs.
No cost-sharing is required.
Applications are due by November 5, 2027.
The earliest submission date is February 11, 2025.
Organizations may submit more than one application, provided each is scientifically distinct.
The NIH will not accept duplicate or overlapping applications under review.
Follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.
Applications must comply with all requirements in the Application Guide.
Applications will be evaluated based on scientific and technical merit.
Reviewers will consider the importance of the research, rigor and feasibility, and expertise and resources.
Applications will undergo peer review by appropriate Scientific Review Groups.
The review process will include a written critique.
Scientific and technical merit of the proposed project.
Relevance of the proposed project to program priorities.
Applications involving human subjects must comply with specific NIH requirements.
Recruitment and retention plans must address barriers to participation.
Applicants must ensure compliance with all application instructions to avoid delays or non-acceptance.
Research should align with NIH priorities and address health disparities.
Strong applications will demonstrate innovative approaches to research and participant recruitment.
Adherence to application guidelines and timelines.
Clear articulation of research significance and innovation.
Submitting overlapping applications.
Failing to comply with registration requirements.
Engage with community partners for recruitment strategies.
Ensure diverse representation in study populations.
Highlight interdisciplinary approaches and potential for significant impact on AD research.