Grant Details

General Overview

Grant Information

Grant name: Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)

Funding organization: National Institutes of Health (NIH)

Total funding amount: Up to $275,000 over two years

Primary objective: Develop next-generation human cell-derived microphysiological systems (MPS) for studying nervous system development and diseases

Key stakeholders: Researchers in biomedical, social, and behavioral fields

Grant program context: Supports exploratory/developmental research

Funding source: Federal government (NIH)

Funding type: Grant

Significance: Addresses complex challenges in understanding nervous system diseases

Grant frequency: One-time funding opportunity

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Small Businesses

Local Governments

State Governments

County Governments

City or Township Governments

Indian/Native American Tribal Governments (Federally Recognized)

Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Governments

U.S. Territory or Possession

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Faith-based or Community-based Organizations

Regional Organizations

Non-domestic (non-U.S.) Entities (Foreign Organizations)

Scope and Focus

Primary Focus Areas

Development of microphysiological systems (MPS) that replicate nervous system architectures

Research on aging and diseases of the nervous system

Encouragement of high-risk, high-reward projects

Technical Details

Technical Expertise Requirements

Collaboration among experts in developmental biology, neuroscience, materials science, and engineering

Financial Structure

Budget and Funding Limits

Combined budget for direct costs may not exceed $275,000 over two years

No more than $200,000 may be requested in any single year

Timeline and Implementation

Key Dates

Open Date: January 16, 2025

Application Due Dates: February 16, 2025; June 16, 2025; October 16, 2025

Expiration Date: January 8, 2026

Compliance and Requirements

Regulatory Compliance

Compliance with NIH Grants Policy Statement

Adherence to ethical standards and regulations

Application Process

Required Documentation

Follow instructions in the Research (R) Instructions in the How to Apply - Application Guide

Grant Details

healthcare research biomedical aging nervous system microphysiological systems exploratory research developmental biology neuroscience materials science engineering
Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)
PAR-25-199
NIH Grants
EDU NGO ENTERPRISE SME PUBLIC RESEARCH OTHER
US
HEALTHCARE RESEARCH OTHER
IDEA DEVELOPMENT
0-10 11-50 51-250 251-500 500+
SDG3 SDG9
FUNDING RESEARCH_DEVELOPMENT
None
275000.00
None
200000.00
USD
None
Oct. 16, 2025, 10 p.m.
Not specified