Grant Details

General Overview

Grant Information

Grant name: Pragmatic Trials across the Cancer Control Continuum (UG3/UH3 Clinical Trial Required)

Funding organization: National Cancer Institute (NCI), Department of Health and Human Services

Total funding amount: Up to $500,000 per year for UG3 phase; up to $750,000 per year for UH3 phase

Duration: Maximum of 2 years for UG3 phase; maximum of 4 years for UH3 phase

Primary objective: Accelerate development of evidence-based cancer-related interventions

Key stakeholders: Individuals, caregivers, practitioners, organizations, healthcare systems, public health settings, communities, policymakers

Funding source: National Institutes of Health

Funding type: Cooperative agreement

Significance: Addresses gaps in cancer-related interventions for diverse populations

Grant frequency: Recurring

Organizational Aspects

Eligible Organization Types

Higher Education Institutions

Public/State Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits (with and without 501(c)(3) status)

For-Profit Organizations (including Small Businesses)

Local, State, County, and City Governments

Indian/Native American Tribal Governments (both Federally Recognized and not)

Federal Government Agencies

Public Housing Authorities

Faith-based or Community-based Organizations

Regional Organizations

Geographic Location Requirements

Organizations must be based in the U.S.

Foreign organizations are not eligible to apply, but foreign components of U.S. organizations are allowed

Scope and Focus

Primary Focus Areas

Cancer-related interventions across the cancer control continuum

Focus on populations experiencing health disparities

Interventions may include behavioral, technology-mediated, community-based, healthcare delivery, and multilevel interventions

Expected Outcomes

Improvement in cancer-related outcomes such as clinical health outcomes, health status, health behaviors, quality of care, and healthcare utilization

Technical Details

Technical Expertise Requirements

Research team must have multidisciplinary expertise necessary for conducting pragmatic trials

Financial Structure

Budget Limitations

UG3 phase: Maximum of $500,000 in direct costs per year

UH3 phase: Maximum of $750,000 in direct costs per year

Timeline and Implementation

Key Dates

Open Date: January 14, 2025

Application Due Dates: Various deadlines until October 17, 2025

Earliest Start Date: February 14, 2025

Compliance and Requirements

Regulatory Compliance

Must comply with NIH and Office for Human Research Protections (OHRP) policies regarding human subjects

Application Process

Required Documentation

Applications must follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide

Grant Details

cancer clinical trials health disparities healthcare public health research interventions evidence-based pragmatic trials
Pragmatic Trials across the Cancer Control Continuum (UG3/UH3 Clinical Trial Required)
PAR-25-072
National Cancer Institute Funding
EDU NGO ENTERPRISE PUBLIC OTHER
US
HEALTHCARE OTHER
DEVELOPMENT OTHER
OTHER
SDG3
FUNDING RESEARCH_DEVELOPMENT
None
None
500000.00
750000.00
USD
None
Oct. 17, 2025, 10 p.m.
Not specified