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Grant Analysis

Purpose & Target

Core objective: Provide administrative supplements to existing NIH research grants and cooperative agreements to cover increased, unforeseen costs within the approved scope.
Target recipient: Program Directors/Principal Investigators (PDs/PIs) holding specific types of NIH research grants.
Size: Not limited by organizational size; applies to various research entities holding NIH grants.
SECTOR-SPECIFIC: Health and Biomedical Research, defined by the missions of participating NIH Institutes/Centers.
Geographic scope: Predominantly United States, implicitly covers institutions eligible for NIH funding.
Key filtering criteria: Applicant must already hold an existing, eligible NIH research grant or cooperative agreement.
Grant frequency: Recurring, as evidenced by its status as a reissue (PA-20-272 reissues PA-18-591), indicating an ongoing program.

Financial Structure

Funding is provided as 'additional funds' awarded as 'supplements' to existing NIH grants and cooperative agreements.
No specific 'total funding amount' for the overall opportunity is stated.
No 'minimum' or 'maximum' supplement amount is specified; the amount requested must be justified by the unforeseen costs and must be within the parent award's scope.
Funds are specifically for 'increased costs that are within the scope of the approved award, but were unforeseen'.
Examples of eligible costs, when specifically addressed by related notices, include 'Childcare Costs' for Ruth L. Kirschstein National Research Service Award (NRSA) awards and 'Technical and Business Assistance (TABA) Funding' for SBIR/STTR awards.
'Matching fund requirements' and 'co-financing requirements' are not specified in this general announcement.
'Payment schedule and mechanisms' are not detailed, but funds are added to the existing award.
Financial reporting and audit requirements are implied to follow standard NIH grant policies for the parent award.
'Indirect cost policies' are not explicitly stated but generally apply to NIH funding based on the applicant's institution's negotiated rate.
There is 'no guarantee that funds are available' from the awarding IC or for any specific grant.

Eligibility Requirements

Organizational Eligibility

Must be a Program Director/Principal Investigator (PD/PI) of an existing, eligible NIH research grant or cooperative agreement.
Must be affiliated with an institution that is eligible to receive NIH funding (e.g., universities, hospitals, research institutions, non-profit organizations, and some for-profit organizations).
The administrative supplement request must be within the original scope of the existing approved award.
The increased costs must have been unforeseen when the original application or progress report was submitted.

Geographic Eligibility

Not explicitly stated as limited by geography, but applies to institutions typically eligible for NIH funding, which are predominantly in the United States. Participation of the Fogarty International Center (FIC) may allow for supplements to some existing international collaborations.

Technical & Legal Requirements

Applicant's institution must have an eRA Commons ID.
Application must be submitted electronically via NIH ASSIST, an institutional system-to-system (S2S) solution, or Grants.gov Workspace.
All requests are considered 'prior approval requests' and are routed directly to the Grants Management Officer of the parent award.

Exclusion Criteria

Requests for new projects or changes in scope that are not within the approved parent award's original scope are ineligible.
Organizations that do not hold an existing, eligible NIH grant or cooperative agreement are not eligible to apply for this specific supplement.

Application Process

Application Deadlines

'Application Due Date(s)' vary by awarding Institute/Center (IC). Applicants must consult the specific IC's website or applicable Notices of Special Interest (NOSIs) for exact dates.
The overall 'Expiration Date' for this funding opportunity is September 30, 2025.

Submission Process

Applications must be submitted electronically.
Available submission platforms include:
- NIH ASSIST system (for online preparation, submission, and tracking).
- Institutional system-to-system (S2S) solution (for preparation and submission via Grants.gov and eRA Commons).
- Grants.gov Workspace (for preparation and submission via Grants.gov and eRA Commons).
Applications are routed directly to the 'Grants Management Officer' of the parent award.

Required Documentation

Applicants must follow instructions in the 'Application Guide (SF424 (R&R) Application Guide)' except where superseded by this Funding Opportunity Announcement (FOA) or NIH Notices.
Specific 'program-specific instructions' noted in Section IV of the FOA must also be followed.

Pre-Application Steps

Applicants are 'encouraged to discuss potential requests with the awarding IC' prior to submission.
Applicants 'must review the awarding IC's web site' to ensure they meet the IC's specific requirements.

Support Availability

'Application assistance availability' is through direct consultation with the relevant awarding IC.

Post-Award Requirements

'Reporting schedule and frequency' will align with the parent award's existing reporting requirements, including financial reporting.
Compliance with NIH policies and regulations is ongoing throughout the grant period.

Evaluation Criteria

Primary Evaluation Factors

Scope Alignment: The requested supplement must be entirely 'within the scope' of the existing approved parent award. This is a critical, non-negotiable factor.
Unforeseen Costs: The need for the supplement must arise from 'increased costs that were unforeseen' when the original application or grant progress report was submitted.
Mission Alignment: The request must fall within the mission of the participating NIH Institutes/Centers (ICs).
IC-Specific Requirements: Applicants must meet specific requirements and priorities of the relevant awarding IC, which may vary. This includes checking the IC's website for specific guidance or Notices of Special Interest (NOSIs).

No Scientific Merit Review

This funding opportunity states 'Scientific Merit Review: Not Applicable'. Administrative supplements are handled as 'prior approval requests' rather than a competitive scientific peer review process for new grants.

Implicit Factors

Justification: The strength of the justification for the additional funds, demonstrating how they are essential to achieving the approved aims of the parent award.
Financial Need: The demonstrated need for the additional funds due to the unforeseen circumstances.
Programmatic Relevance: How the supplement supports NIH or specific IC programmatic priorities, particularly if linked to a Notice of Special Interest (NOSI).

Compliance & Special Requirements

Regulatory Compliance

Compliance with all applicable federal regulations governing NIH grants is required.
Specific attention is drawn to 'Updates to the Non-Discrimination Legal Requirements for NIH Recipients' (NOT-OD-21-181).
'Electronic Submission' is mandatory for all administrative supplements (NOT-OD-20-128).

Scope and Intent Limitations

The supplement must be strictly 'within the scope' of the original approved research project. This is a critical defining feature.
Funds are intended for 'unforeseen' costs, not for planned expenses or significant expansion beyond the original project's aims.

IC-Specific Variations

'IC-specific submission deadlines, eligibility criteria, or application requirements' exist and must be reviewed on each individual NIH Institute or Center's website. This includes specific policies on administrative supplements and potentially specific 'Notices of Special Interest (NOSIs)'.

Special Supplement Types

Various NIH Institutes/Centers may issue specific NOSIs or guidance for particular types of administrative supplements, such as:
- Supplements for 'childcare costs' (NOT-OD-24-116).
- 'Technical and Business Assistance (TABA) Funding' for SBIR/STTR awards (NOT-OD-24-077).
- Supplements to promote 'Diversity in Health-Related Research'.
- Supplements to promote 'Reentry into Biomedical and Behavioral Research Careers'.
- Supplements for specific research areas like 'Pain-Focused' research (e.g., NOT-NS-22-053).

Risk and Guarantee

There is 'no guarantee' that funds will be available or awarded, even if the application meets criteria. This remains a 'prior approval' process at the IC's discretion.

Grant Details