Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions
National Institutes of Health (NIH)
Total funding amount is $27,000,000 for FY 2026.
The project period may not exceed three years.
The mission is to transform the understanding and treatment of mental illnesses through research.
The primary objective is to support pilot studies that evaluate the effectiveness of mental health interventions.
Mental health researchers and practitioners.
Individuals with mental health conditions, particularly those in underserved communities.
Eligible organizations include higher education institutions, nonprofits, for-profit organizations, small businesses, local, state, and federal governments, and tribal governments.
Non-domestic entities (foreign organizations) are also eligible.
Organizations from the United States and foreign entities are eligible to apply.
Projects must focus on pilot hybrid effectiveness implementation trials.
Research should address mental health interventions and implementation strategies.
Direct costs are limited to $750,000 over the project period, with no more than $250,000 in any single year.
Applications are due by October 15, 2027.
The earliest submission date is January 14, 2025.
Applicants may submit more than one application as long as each is scientifically distinct.
Applications must follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.
Applications will be evaluated based on significance, innovation, and approach.
Applications will undergo peer review and be evaluated for scientific and technical merit.
Priority will be given to applications that address mental health disparities and improve access to services.
The grant requires a clinical trial design and evaluation of mechanisms of action.
Applications that do not propose a hybrid effectiveness implementation trial design will not be reviewed.
Encouragement to address mental health disparities and optimize interventions in under-resourced settings.
Utilizing existing infrastructure for data collection may enhance the feasibility of the proposed research.
Incorporating community and practice partner perspectives in the research design.
Avoid proposing adaptations of existing interventions without empirical justification.
Engage with community partners early in the research design process.
Highlight innovative aspects of the proposed research and its potential impact on mental health outcomes.