Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional)
National Institutes of Health (NIH)
Maximum project period of 2 years
Combined budget for direct costs may not exceed $275,000
To invite applications proposing new tests, animal models, techniques, etc. to advance research on Alzheimer's disease (AD) and its related dementias (ADRD).
To encourage biomedical, social, and behavioral research directed toward greater understanding of aging and related diseases.
Researchers in the field of Alzheimer's and dementia.
Individuals affected by Alzheimer's disease and related dementias.
Eligible organization types include Higher Education Institutions, Nonprofits, For-Profit Organizations, Local Governments, State Governments, County Governments, City or Township Governments, Indian/Native American Tribal Governments, and Federal Governments.
Foreign organizations are eligible to apply.
Open to U.S. and non-domestic (foreign) entities.
Proposals must advance research on Alzheimer's disease and related dementias.
Projects should generate preliminary data for broader dissemination.
The combined budget for direct costs may not exceed $275,000.
No more than $200,000 in direct costs may be requested in any single year.
Application due dates are set for various cycles, with the next due date on November 16, 2027.
Applicants may submit more than one application, provided each is scientifically distinct.
Applications must follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.
Applications will be evaluated for scientific and technical merit through the NIH peer review system.
Applications will undergo a selection process based on scientific merit and relevance to program priorities.
Overall impact, significance, innovation, rigor, and feasibility will be considered.
The grant allows for optional clinical trials.
Applications must comply with all submission guidelines to avoid delays or rejection.
Projects should align with NIH's strategic priorities for Alzheimer's research.
Strong proposals that address health disparities may have a competitive advantage.
Demonstrating innovative approaches and potential for significant impact on AD research.
Failure to adhere to application guidelines and submission deadlines.
Engage with community partners to enhance recruitment and retention strategies.
Highlighting interdisciplinary collaboration and addressing health disparities can strengthen applications.