Ancillary Studies to Ongoing Clinical Projects (R01 Clinical Trial Not Allowed)
National Institutes of Health (NIH)
Maximum funding amount: $300,000 per year
Project duration: Up to four years
To support time-sensitive ancillary studies related to ongoing clinical projects.
Enhance scientific understanding of diseases within the NIAMS portfolio.
NIH and its associated institutes.
Research community and patients involved in clinical studies.
Eligible organization types include higher education institutions, nonprofits, for-profit organizations, local and state governments, and tribal governments.
Non-domestic (non-U.S.) entities are not eligible to apply.
U.S. organizations are eligible; foreign organizations are generally excluded.
Projects must be ancillary to ongoing clinical studies or trials.
Must leverage existing resources from parent projects.
Budgets for direct costs are limited to $300,000 per year.
No cost-sharing is required.
Application due date: December 5, 2025.
Letter of intent due 30 days prior to application due date.
Applications must not overlap with previously submitted applications.
Applications must include a letter of approval from the parent study leadership committee.
A detailed timeline and justification for the time-sensitive nature of the study.
Applications will be evaluated based on significance, innovation, rigor, and feasibility.
Accelerated review and award process for time-sensitive applications.
Scientific merit and relevance to NIAMS mission.
Encourages collaboration between basic and clinical researchers.
Applications must demonstrate the need for expedited review.
Aligns with NIH's mission to enhance health through research.
Applications with strong ties to ongoing clinical projects may have a competitive edge.
Demonstrating the scientific rationale for the ancillary study.
Submitting applications that do not clearly justify the need for expedited review.
Engage with senior investigators for support and collaboration.
Highlight unique aspects of the parent project that enhance the ancillary study.