Grant Details

GRANT OVERVIEW

Grant name and funding organization

PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications

Funding organization: National Institutes of Health (NIH)

Total funding amount and duration

Total funding support for Phase I awards may not exceed $306,872

Total funding support for Phase II awards may not exceed $2,045,816

Award periods normally may not exceed 1 year for Phase I and 2 years for Phase II

Primary objective and mission statement

To invite eligible United States small businesses to submit STTR grant applications

To support research and development that has strong potential for commercialization

Key stakeholders and beneficiaries

United States small business concerns (SBCs)

NIH awarding components

ELIGIBILITY CRITERIA

Organization Requirements

Only United States small business concerns (SBCs) are eligible to apply

SBCs must be organized for profit and have a place of business located in the United States

SBCs must be more than 50% owned and controlled by U.S. citizens or permanent resident aliens

Geographic Scope

Eligible organizations must be located in the United States

Non-domestic (non-U.S.) entities are not eligible to apply

Project Requirements

Projects must not propose clinical trials

Applications must demonstrate potential for commercialization

Financial Requirements

Total funding support for Phase I and Phase II awards is specified

No cost sharing is required

Timeline Requirements

Applications are due by 5:00 PM local time of applicant organization

Key deadlines include September 5, 2025, for the latest application submission

Previous Funding Considerations

SBCs must meet performance benchmarks related to Phase I to Phase II transition rates

APPLICATION PROCESS

Required documentation and materials

Applications must follow the SBIR/STTR (B) Instructions in the How to Apply – Application Guide

Specific forms and documentation as outlined in the application guide must be submitted

Evaluation criteria and scoring system

Applications will be evaluated based on scientific and technical merit

Review criteria include significance, innovation, approach, and environment

Review process and timeline

Applications will undergo peer review and be assigned an overall impact score

Second level of review by the appropriate national Advisory Council or Board

Selection criteria and priorities

Relevance of the proposed project to program priorities will be considered

Availability of funds will also influence funding decisions

SPECIAL CONSIDERATIONS

Unique aspects or requirements

Applications must not propose clinical trials

SBCs must secure substantial independent third-party investor funds

Potential challenges or limitations

Non-domestic entities and components are not eligible to apply

SBCs must meet specific performance benchmarks to maintain eligibility

Strategic alignment opportunities

Projects that align with NIH's mission to improve health and save lives are prioritized

Competitive advantages or disadvantages

SBCs with a strong commercialization plan may have a competitive advantage

KEY INSIGHTS AND RECOMMENDATIONS

Critical success factors

Demonstrating strong potential for commercialization is crucial

Adhering to application guidelines and deadlines is essential

Common pitfalls to avoid

Submitting applications that do not comply with the guidelines

Failing to secure necessary registrations in advance

Strategic recommendations for applicants

Engage with program officials early in the application process

Ensure all required registrations are completed before submission

Competitive positioning advice

Highlight unique aspects of the proposed project that align with NIH priorities

Demonstrate the ability to secure third-party funding

Grant Details

small business technology transfer healthcare research and development commercialization NIH funding opportunity innovation grants
PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
PA-24-247
NIH STTR
None
None
306872.00
2045816.00
USD
None
Sept. 5, 2025, 9 p.m.
November 2025 - January 2026