Grant name: Ex Vivo Models for Studies at the Intersection of HIV and Addictive Substance Use
Funding organization: National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA)
Total funding amount: $2,000,000
Duration: Maximum project period of 5 years
Primary objective: To elucidate neuroimmune and neuronal-glial mechanisms underlying the interaction between addictive substances and HIV-associated neurological disorders.
Funding source: Federal government
Significance: Addresses critical gaps in understanding HIV neuropathology and substance use interactions.
Grant frequency: One-time funding opportunity.
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
For-Profit Organizations
Small Businesses
Local Governments
State Governments
County Governments
City or Township Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Foreign Organizations
Organizations must complete registrations with SAM, eRA Commons, and Grants.gov.
All Program Directors/Principal Investigators must have an eRA Commons account.
Mechanisms of HIV neuropathogenesis in the presence of addictive substances.
Impact of addictive substances on HIV-associated neurological disorders.
Use of ex vivo culturing platforms derived from human induced pluripotent stem cells (hiPSC).
Research must utilize human cells or tissues.
Applications must focus on the interaction of HIV and addictive substances.
Application budgets are not limited but must reflect the actual needs of the proposed project.
Open Date: July 13, 2025
Application Due Date: July 13, 2025
Earliest Start Date: August 13, 2025
Expiration Date: August 14, 2025
Applications must comply with NIH Grants Policy Statement.
No clinical trials are allowed.
Applications must be submitted electronically via Grants.gov.
Follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide.
Applications not using human cells or tissues will be withdrawn.
Applications focusing solely on alcohol exposure will be considered non-responsive.